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    Methodica Research Course

    Methodica is a blended learning course designed to provide medical students and healthcare professionals with a strong foundation in clinical research methodology. The course combines self-paced online learning with interactive, hands-on workshops to bridge the gap between research theory and practice. Participants will learn the fundamentals of clinical research, study designs, sampling methods, hypothesis development, research documentation, sample size estimation, and the basics of clinical trials. Practical workshops focus on case report writing, sample size calculation, protocol development, and clinical trial applications. Upon successful completion of the online modules and workshops, participants join supervised research groups to collaboratively develop a research project under the guidance of experienced mentors, enabling them to apply their knowledge in real-world scientific research.

    Ashraf Nabhan Course byAshraf Nabhan
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    Methodica (Primary Studies)
    Official MedC course

    Included with enrollment

    Videos · PDFs · Exams

    Enrollment

    EGP 2,000

    238

    Learners

    15 h

    Study time

    EGP 2,000

    Enrollment

    Course overview

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    Review the course, explore the curriculum, and speak directly with MedC when you are ready to enroll.

    Methodica is a blended learning course designed to provide medical students and healthcare professionals with a strong foundation in clinical research methodology. The course combines self-paced online learning with interactive, hands-on workshops to bridge the gap between research theory and practice. Participants will learn the fundamentals of clinical research, study designs, sampling methods, hypothesis development, research documentation, sample size estimation, and the basics of clinical trials. Practical workshops focus on case report writing, sample size calculation, protocol development, and clinical trial applications. Upon successful completion of the online modules and workshops, participants join supervised research groups to collaboratively develop a research project under the guidance of experienced mentors, enabling them to apply their knowledge in real-world scientific research.

    Clear curriculum

    3 learning formats

    Expert-led

    By Ashraf Nabhan

    Direct support

    Enrollment help on WhatsApp

    Learning outcomes

    Finish with skills you can put into practice.

    A focused learning journey with outcomes you can understand before you enroll.

    fundamentals of clinical research

    population selection, sampling, and sample size estimation

    Formulate research hypotheses and define study variables

    Identify essential research documentation

    Differentiate major observational study designs and diagnostic accuracy studies

    Describe the fundamentals of clinical trials

    Prepare a clinical case report

    Develop a high-quality research protocol

    Collaborate effectively in a supervised research project

    Inside the course

    Explore the complete curriculum.

    See the published Medical Library articles, videos, resources, question banks, Essay Books, exams, and revision tools included with this course.

    49 published items

    Videos

    31

    31 videos included

    Video12 min

    1. Introduction to Fundamentals of Clinical Research

    • What makes clinical research useful (informative, reproducible, verifiable) • Primary and secondary research

    Video13 min

    2. Anatomy and Physiology of Research

    • Anatomy and Physiology of Research • Types of clinical research questions • Purpose of Research: answering a clear question

    Video12 min

    3. Common sense in Research

    • Common sense • Evidence, uncertainty, hypothesis formation

    Video5 min

    5. Population vs sampling

    Population vs sampling; parameters vs statistics • inclusion and exclusion criteria

    Video14 min

    6. Target population

    • Target population -> accessible population -> sample • Recruitment strategies • Homogeneity vs Generalizability

    Video5 min

    4. Types of hypotheses

    Types of hypotheses (simple, specific, a priori)

    Video11 min

    7. Introduction to variables

    • What is a variable? • types: independent, dependent, extraneous/ confounding • identifying confounders

    Video9 min

    8. Examples on the variables and confounder

    • Practice examples (Endgames)

    Video10 min

    9. Introduction to Measurement and Data

    • Types of data • Enhancing measurements: standardization, training, automation, masking • Precision vs accuracy • Endgames (identifying variable types, parameters, observations)

    Video12 min

    10. Hypothesis and its components

    • How to write a research hypothesis • Components: parameter, hypothesized value, direction • Null hypotheses for: one mean, two means, paired means, one proportion, two proportions, correlation

    Video13 min

    11. Sampling methods

    • sampling methods: convenience, consecutive, simple random, systematic, stratified, cluster

    Video16 min

    12. Sample size calculations

    • Typical sample sizes in trials • common sample-size mistakes • elements needed for sample sizes calculation: N, P, confidence, error margin • practical R- based examples

    Video12 min

    13. Introduction to cross-sectional studies (part 1)

    • describes variables • prevalence

    Video10 min

    14. Special types (part 2)

    Special types: serial and pseudo-cohort

    Video9 min

    15. Bias (part 3)

    • Bias in XS studies: Misclassification, Reverse causality

    Video14 min

    17. Incidence and prospective cohort study

    • Measure incidence and show temporal sequence • prospective cohort study

    Video17 min

    16. Overview, importance and bias of Case-Control Studies

    • select based on disease status • good for rare diseases and long latency • cannot estimate incidence; risk of selection and recall bias

    Video10 min

    18. Retrospective and inception cohort

    • Retrospective cohort study • inception cohort • Bias: Affected by loss to follow-up and misclassification

    Video11 min

    19. Eligibility criteria and sampling

    • Diagnostic Test Accuracy Studies • Eligibility criteria • sampling

    Video10 min

    20. Index test

    • index test • Designing and conducting DTA studies

    Video9 min

    21. DTA measures

    • one gate design • measures: sensitivity, specificity, PPV, NPV, likelihood ratios • Bias

    Video11 min

    1. What makes a clinical trial ethical?

    Value, validity, favourable risk benefit ratio, independent review, informed consent

    Video12 min

    2. Trial design

    Prospective registration, trial design including types, framework, allocation, controlled and phases

    Video12 min

    3. Random allocation part 1

    Controlled clinical study, Random Allocation: allocation vs sampling, methods, sequence generation

    Video12 min

    4. Random allocation part 2

    Sequence generation: block and stratified, allocation concealment

    Video8 min

    5. Blinding

    Candidates for blinding

    Video7 min

    6. Maximize Adherence

    Convenience, choose subjects, encouragement

    Video14 min

    7. Unit of Allocation

    A participant vs cluster of participants, adaptive design

    Video10 min

    9. Bias in Clinical Trials

    Selection bias, Information bias

    Video14 min

    8. NI trials

    Value of Delta, non-significance ≠ non-inferior

    Video2.2 h

    Critical examination of a paper

    The link to the magnificent state of the art paper https://link.springer.com/article/10.1007/s11916-023-01208-0 start today by drafting a critical examination of this remarkable paper.

    PDFs

    17

    17 PDFs included

    PDFPDF

    1. Anatomy and Physiology

    Getting Started: The Anatomy and Physiology of Clinical Research .......................................... 2 Stephen B. Hulley, Thomas B. Newman, and Steven R. Cumming

    PDFPDF

    2. Research Question & Development of a Study Plan

    Conceiving the Research Question and Developing the Study Plan

    PDFPDF

    3. Choosing the Study Subjects

    Choosing the Study Subjects: Specification, Sampling, and Recruitment

    PDFPDF

    4. Planning the Measurements

    Planning the Measurements: Precision, Accuracy, and Validity

    PDFPDF

    5. Sample Size

    Getting Ready to Estimate Sample Size: Hypotheses and Underlying Principles.

    PDFPDF

    6.1 Estimating Sample Size

    Estimating Sample Size and Power: Applications and Examples

    PDFPDF

    6.2 Applications and Examples

    Estimating Sample Size and Power: Applications and Examples

    PDFPDF

    PowerPoint presentation

    Presentation by Dr. Ashraf

    PDFPDF

    7. Cross sectional and cohort

    Cross sectional and cohort

    PDFPDF

    8. Case-control studies

    Case-control

    PDFPDF

    9. Designing studies of Medical tests

    Medical tests &

    PDFPDF

    What is a case control study

    What is a case control study

    PDFPDF

    Protocol training

    protocol training

    PDFPDF

    1. Clinical trials

    Implementation

    PDFPDF

    Clinical trials 2

    Clinical trials 2

    PDFPDF

    Clinical trials 3

    Clinical trials 3

    PDFPDF

    Designing clinical research

    Designing clinical research

    Exams

    1

    1 exam included

    Exam30 min

    Methodica Mock Exam 1

    Methodica Mock Exam 1

    Designed for

    Is this course for you?

    - Medical students - Medical interns - Resident doctors - General practitioners - Healthcare professionals interested in clinical research and evidence-based medicine

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    EGP 2,000

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